SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02051

Signal sequence   MRLSLLLALLALLALASLALAAP

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02051.cif

Structure  SPKB02051.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2318.97344

Aliphatic index  216.9565217

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  797.09

Aromaticity  0

Average rotatable bonds  3.260869565

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -1.78253

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.