SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02047

Signal sequence   APIPLVANVSFNSDNGSQWLYKREEGEPK

Length  29

Organism  Artificial

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02047.cif

Structure  SPKB02047.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3246.58344

Aliphatic index  67.24137931

Isoelectric point  4.587621972

Charge (pH=7)   -0.997687641

Topological polar surface area  1383.96

Aromaticity  0.103448276

Average rotatable bonds  3.551724138

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  45

X logP energy  -14.38183

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.