SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02046

Signal sequence   APIPLVANVSFNSDNGSQWLYKRDVVYPK

Length  29

Organism  Artificial

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02046.cif

Structure  SPKB02046.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3278.71484

Aliphatic index  87.24137931

Isoelectric point  9.121157886

Charge (pH=7)   0.99658306

Topological polar surface area  1329.59

Aromaticity  0.137931034

Average rotatable bonds  3.448275862

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  44

X logP energy  -11.87263

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.