SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02043

Signal sequence   SYSRVSNAAGKSRGDCRSRLFPDGTKSPPSASPRREARRDSLHPVLTSSAESGSGYMSSNSARDLLRSGAKNHLGAPNNDQVKFGLATRTRKRAE

Length  96

Organism  Artificial

UniProt ID  NA,

Motif  1..96



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02043.cif

Structure  SPKB02043.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  10204.24804

Aliphatic index  48.42105263

Isoelectric point  11.66426851

Charge (pH=7)   10.12216651

Topological polar surface area  4760.37

Aromaticity  0.042105263

Average rotatable bonds  3.589473684

Number of hydrogen bond donors  174

Number of hydrogen bond acceptors  155

X logP energy  -72.38569

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.