SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02040

Signal sequence   PSVRPPVASRDYSHSARWSTKKRSRR

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02040.cif

Structure  SPKB02040.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3068.45454

Aliphatic index  30

Isoelectric point  12.51217355

Charge (pH=7)   7.087879525

Topological polar surface area  1426.3

Aromaticity  0.076923077

Average rotatable bonds  3.769230769

Number of hydrogen bond donors  56

Number of hydrogen bond acceptors  45

X logP energy  -19.40778

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.