SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02038

Signal sequence   MKSSSLLLLALLALLAALASAAP

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02038.cif

Structure  SPKB02038.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2238.79764

Aliphatic index  183.0434783

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  801.67

Aromaticity  0

Average rotatable bonds  3.173913043

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -5.0244

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.