SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02020

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLEKR

Length  66

Organism  Artificial

UniProt ID  NA,

Motif  1..66



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6KRL,

Predicted Structure ID  SPKB02020.cif

Structure  SPKB02020.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6956.64114

Aliphatic index  93.18181818

Isoelectric point  3.683666447

Charge (pH=7)   -7.989247698

Topological polar surface area  2974.22

Aromaticity  0.060606061

Average rotatable bonds  3.439393939

Number of hydrogen bond donors  99

Number of hydrogen bond acceptors  100

X logP energy  -34.72563

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.