SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01970

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLKEGEPK

Length  69

Organism  Artificial

UniProt ID  NA,

Motif  1..69



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01970.cif

Structure  SPKB01970.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7211.91184

Aliphatic index  89.13043478

Isoelectric point  3.639786116

Charge (pH=7)   -8.987764298

Topological polar surface area  3054.15

Aromaticity  0.057971014

Average rotatable bonds  3.405797101

Number of hydrogen bond donors  100

Number of hydrogen bond acceptors  104

X logP energy  -35.4031

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.