SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01964

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLKREEEK

Length  69

Organism  Artificial

UniProt ID  NA,

Motif  1..69



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01964.cif

Structure  SPKB01964.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7343.04624

Aliphatic index  89.13043478

Isoelectric point  3.746894096

Charge (pH=7)   -8.985992486

Topological polar surface area  3162.14

Aromaticity  0.057971014

Average rotatable bonds  3.52173913

Number of hydrogen bond donors  105

Number of hydrogen bond acceptors  106

X logP energy  -36.41263

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.