SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01870

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDREEK

Length  68

Organism  Artificial

UniProt ID  NA,

Motif  1..68



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01870.cif

Structure  SPKB01870.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7200.84524

Aliphatic index  90.44117647

Isoelectric point  3.585852047

Charge (pH=7)   -9.987026091

Topological polar surface area  3107.02

Aromaticity  0.058823529

Average rotatable bonds  3.470588235

Number of hydrogen bond donors  103

Number of hydrogen bond acceptors  104

X logP energy  -36.41653

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.