SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01841

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLEEEP

Length  67

Organism  Artificial

UniProt ID  NA,

Motif  1..67



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6KRL,

Predicted Structure ID  SPKB01841.cif

Structure  SPKB01841.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7027.62724

Aliphatic index  91.79104478

Isoelectric point  3.211345817

Charge (pH=7)   -11.98539911

Topological polar surface area  2981.21

Aromaticity  0.059701493

Average rotatable bonds  3.373134328

Number of hydrogen bond donors  97

Number of hydrogen bond acceptors  101

X logP energy  -34.3973

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.