SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01837

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLRGPK

Length  67

Organism  Artificial

UniProt ID  NA,

Motif  1..67



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6KRL,

Predicted Structure ID  SPKB01837.cif

Structure  SPKB01837.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6981.69424

Aliphatic index  91.79104478

Isoelectric point  3.733183784

Charge (pH=7)   -6.991022821

Topological polar surface area  2957.23

Aromaticity  0.059701493

Average rotatable bonds  3.358208955

Number of hydrogen bond donors  98

Number of hydrogen bond acceptors  100

X logP energy  -34.96803

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.