SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01791

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDREP

Length  67

Organism  Artificial

UniProt ID  NA,

Motif  1..67



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01791.cif

Structure  SPKB01791.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7040.67234

Aliphatic index  91.79104478

Isoelectric point  3.449150084

Charge (pH=7)   -9.98850618

Topological polar surface area  3005.81

Aromaticity  0.059701493

Average rotatable bonds  3.373134328

Number of hydrogen bond donors  99

Number of hydrogen bond acceptors  101

X logP energy  -35.38893

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.