SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01777

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDKRE

Length  67

Organism  Artificial

UniProt ID  NA,

Motif  1..67



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01777.cif

Structure  SPKB01777.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7071.72974

Aliphatic index  91.79104478

Isoelectric point  3.624238253

Charge (pH=7)   -8.988801214

Topological polar surface area  3040.62

Aromaticity  0.059701493

Average rotatable bonds  3.447761194

Number of hydrogen bond donors  101

Number of hydrogen bond acceptors  102

X logP energy  -35.76613

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.