SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01730

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDKE

Length  66

Organism  Artificial

UniProt ID  NA,

Motif  1..66



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01730.cif

Structure  SPKB01730.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6915.54224

Aliphatic index  93.18181818

Isoelectric point  3.449150078

Charge (pH=7)   -9.988797903

Topological polar surface area  2949.62

Aromaticity  0.060606061

Average rotatable bonds  3.409090909

Number of hydrogen bond donors  97

Number of hydrogen bond acceptors  100

X logP energy  -34.5142

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.