SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01726

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLGP

Length  65

Organism  Artificial

UniProt ID  NA,

Motif  1..65



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6KRL,

Predicted Structure ID  SPKB01726.cif

Structure  SPKB01726.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6697.33264

Aliphatic index  94.61538462

Isoelectric point  3.311571952

Charge (pH=7)   -8.990724476

Topological polar surface area  2811.11

Aromaticity  0.061538462

Average rotatable bonds  3.276923077

Number of hydrogen bond donors  92

Number of hydrogen bond acceptors  96

X logP energy  -33.3299

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.