SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01720

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLRK

Length  65

Organism  Artificial

UniProt ID  NA,

Motif  1..65



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01720.cif

Structure  SPKB01720.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6827.52564

Aliphatic index  94.61538462

Isoelectric point  3.733183784

Charge (pH=7)   -6.991022821

Topological polar surface area  2907.82

Aromaticity  0.061538462

Average rotatable bonds  3.415384615

Number of hydrogen bond donors  97

Number of hydrogen bond acceptors  98

X logP energy  -34.07523

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.