SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01711

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDP

Length  65

Organism  Artificial

UniProt ID  NA,

Motif  1..65



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01711.cif

Structure  SPKB01711.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6755.36934

Aliphatic index  94.61538462

Isoelectric point  3.25910167

Charge (pH=7)   -9.990277991

Topological polar surface area  2848.41

Aromaticity  0.061538462

Average rotatable bonds  3.307692308

Number of hydrogen bond donors  93

Number of hydrogen bond acceptors  97

X logP energy  -33.4866

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.