SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01702

Signal sequence   APVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLK

Length  64

Organism  Artificial

UniProt ID  NA,

Motif  1..64



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01702.cif

Structure  SPKB01702.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6671.33814

Aliphatic index  96.09375

Isoelectric point  3.544784796

Charge (pH=7)   -7.991019509

Topological polar surface area  2816.82

Aromaticity  0.0625

Average rotatable bonds  3.375

Number of hydrogen bond donors  93

Number of hydrogen bond acceptors  96

X logP energy  -32.8233

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.