SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01698

Signal sequence   STLTPSVVFIGGGLTEETTFGIRHKRDV

Length  28

Organism  Artificial

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01698.cif

Structure  SPKB01698.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3018.41984

Aliphatic index  86.78571429

Isoelectric point  7.551317816

Charge (pH=7)   0.092588463

Topological polar surface area  1272.24

Aromaticity  0.071428571

Average rotatable bonds  3.5

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  43

X logP energy  -14.12826

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.