SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01693

Signal sequence   IPLVANVSFNSDNGSQWLYKRVVYPK

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01693.cif

Structure  SPKB01693.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2995.43074

Aliphatic index  93.46153846

Isoelectric point  9.928544783

Charge (pH=7)   1.996136576

Topological polar surface area  1213.78

Aromaticity  0.153846154

Average rotatable bonds  3.576923077

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  40

X logP energy  -10.32783

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.