SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01692

Signal sequence   IPLVANVSFNSDNGSQWLYKRDVYPK

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01692.cif

Structure  SPKB01692.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3011.38674

Aliphatic index  82.30769231

Isoelectric point  9.121157886

Charge (pH=7)   0.99658306

Topological polar surface area  1251.08

Aromaticity  0.153846154

Average rotatable bonds  3.615384615

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  41

X logP energy  -11.50913

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.