SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01690

Signal sequence   IPLVANVSFNSDNGSQWLYKRDVVYK

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01690.cif

Structure  SPKB01690.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3013.40264

Aliphatic index  93.46153846

Isoelectric point  9.121157886

Charge (pH=7)   0.99658306

Topological polar surface area  1259.87

Aromaticity  0.153846154

Average rotatable bonds  3.692307692

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  41

X logP energy  -11.35933

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.