SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01687

Signal sequence   IPLVANVSFNSDNGSQWLYRVVYPK

Length  25

Organism  Artificial

UniProt ID  NA,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01687.cif

Structure  SPKB01687.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2867.25664

Aliphatic index  97.2

Isoelectric point  9.145093667

Charge (pH=7)   0.99643161

Topological polar surface area  1158.66

Aromaticity  0.16

Average rotatable bonds  3.48

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  38

X logP energy  -9.94163

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.