SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01680

Signal sequence   IPLVANVSFNSDNGSQWLYKDVVPK

Length  25

Organism  Artificial

UniProt ID  NA,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01680.cif

Structure  SPKB01680.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2791.15584

Aliphatic index  97.2

Isoelectric point  6.440547229

Charge (pH=7)   -0.002563214

Topological polar surface area  1139.85

Aromaticity  0.12

Average rotatable bonds  3.48

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  38

X logP energy  -10.5495

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.