SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01648

Signal sequence   IPLVANVSFNSDNGSQWLYKVVYK

Length  24

Organism  Artificial

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01648.cif

Structure  SPKB01648.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2742.12654

Aliphatic index  101.25

Isoelectric point  9.121616307

Charge (pH=7)   0.996139887

Topological polar surface area  1102.47

Aromaticity  0.166666667

Average rotatable bonds  3.583333333

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  37

X logP energy  -9.0669

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.