SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01647

Signal sequence   IPLVANVSFNSDNGSQWLYKVVYP

Length  24

Organism  Artificial

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01647.cif

Structure  SPKB01647.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2711.06914

Aliphatic index  101.25

Isoelectric point  6.324009879

Charge (pH=7)   -0.003565079

Topological polar surface area  1067.66

Aromaticity  0.166666667

Average rotatable bonds  3.375

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  36

X logP energy  -8.6897

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.