SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01646

Signal sequence   IPLVANVSFNSDNGSQWLYKDYPK

Length  24

Organism  Artificial

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01646.cif

Structure  SPKB01646.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2756.06664

Aliphatic index  77.08333333

Isoelectric point  6.433998661

Charge (pH=7)   -0.003413628

Topological polar surface area  1130.98

Aromaticity  0.166666667

Average rotatable bonds  3.541666667

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  38

X logP energy  -10.398

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.