SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01638

Signal sequence   IPLVANVSFNSDNGSQWLYKRVPK

Length  24

Organism  Artificial

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01638.cif

Structure  SPKB01638.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2733.12214

Aliphatic index  89.16666667

Isoelectric point  10.24365751

Charge (pH=7)   1.99698699

Topological polar surface area  1135.35

Aromaticity  0.125

Average rotatable bonds  3.583333333

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  37

X logP energy  -10.90173

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.