SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01615

Signal sequence   IPLVANVSFNSDNGSQWLYDVVY

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01615.cif

Structure  SPKB01615.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2600.86694

Aliphatic index  105.6521739

Isoelectric point  3.491881174

Charge (pH=7)   -2.002823561

Topological polar surface area  1058.63

Aromaticity  0.173913043

Average rotatable bonds  3.391304348

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  35

X logP energy  -9.335

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.