SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01614

Signal sequence   IPLVANVSFNSDNGSQWLYRVPK

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01614.cif

Structure  SPKB01614.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2604.94804

Aliphatic index  93.04347826

Isoelectric point  9.297356245

Charge (pH=7)   0.997282024

Topological polar surface area  1080.23

Aromaticity  0.130434783

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  35

X logP energy  -10.51553

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.