SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01601

Signal sequence   IPLVANVSFNSDNGSQWLYKVPK

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01601.cif

Structure  SPKB01601.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2576.93464

Aliphatic index  93.04347826

Isoelectric point  9.256043355

Charge (pH=7)   0.996990302

Topological polar surface area  1044.35

Aromaticity  0.130434783

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  35

X logP energy  -9.6498

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.