SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01600

Signal sequence   IPLVANVSFNSDNGSQWLYKVYK

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01600.cif

Structure  SPKB01600.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2642.99394

Aliphatic index  93.04347826

Isoelectric point  9.121616307

Charge (pH=7)   0.996139887

Topological polar surface area  1073.37

Aromaticity  0.173913043

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  36

X logP energy  -9.2077

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.