SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01597

Signal sequence   IPLVANVSFNSDNGSQWLYKVVP

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01597.cif

Structure  SPKB01597.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2547.89314

Aliphatic index  105.6521739

Isoelectric point  6.330585692

Charge (pH=7)   -0.002714665

Topological polar surface area  1018.33

Aromaticity  0.130434783

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -9.1228

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.