SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01584

Signal sequence   IPLVANVSFNSDNGSQWLYKRVY

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01584.cif

Structure  SPKB01584.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2671.00734

Aliphatic index  93.04347826

Isoelectric point  9.145093667

Charge (pH=7)   0.99643161

Topological polar surface area  1109.25

Aromaticity  0.173913043

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  36

X logP energy  -10.07343

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.