SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01572

Signal sequence   IPLVANVSFNSDNGSQWLYVVY

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01572.cif

Structure  SPKB01572.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2485.77834

Aliphatic index  110.4545455

Isoelectric point  3.749986565

Charge (pH=7)   -1.003270045

Topological polar surface area  992.23

Aromaticity  0.181818182

Average rotatable bonds  3.363636364

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  -8.2945

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.