SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01566

Signal sequence   IPLVANVSFNSDNGSQWLYDVY

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01566.cif

Structure  SPKB01566.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2501.73434

Aliphatic index  97.27272727

Isoelectric point  3.491881174

Charge (pH=7)   -2.002823561

Topological polar surface area  1029.53

Aromaticity  0.181818182

Average rotatable bonds  3.409090909

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  34

X logP energy  -9.4758

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.