SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01557

Signal sequence   IPLVANVSFNSDNGSQWLYRDV

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01557.cif

Structure  SPKB01557.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2494.74584

Aliphatic index  97.27272727

Isoelectric point  4.109250254

Charge (pH=7)   -1.001976458

Topological polar surface area  1071.2

Aromaticity  0.136363636

Average rotatable bonds  3.5

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  34

X logP energy  -11.16083

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.