SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01555

Signal sequence   IPLVANVSFNSDNGSQWLYKVP

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01555.cif

Structure  SPKB01555.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2448.76054

Aliphatic index  97.27272727

Isoelectric point  6.330585692

Charge (pH=7)   -0.002714665

Topological polar surface area  989.23

Aromaticity  0.136363636

Average rotatable bonds  3.363636364

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -9.2636

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.