SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01527

Signal sequence   IPLVANVSFNSDNGSQWLYKREEGEPK

Length  27

Organism  Artificial

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01527.cif

Structure  SPKB01527.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3078.38794

Aliphatic index  68.51851852

Isoelectric point  4.587621972

Charge (pH=7)   -0.997687641

Topological polar surface area  1334.55

Aromaticity  0.111111111

Average rotatable bonds  3.703703704

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  43

X logP energy  -13.87753

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.