SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01525

Signal sequence   IPLVANVSFNSDNGSQWLYKEEGEPK

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01525.cif

Structure  SPKB01525.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2922.20044

Aliphatic index  71.15384615

Isoelectric point  4.147551664

Charge (pH=7)   -1.99768433

Topological polar surface area  1243.55

Aromaticity  0.115384615

Average rotatable bonds  3.615384615

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  41

X logP energy  -12.6256

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.