SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01524

Signal sequence   IPLVANVSFNSDNGSQWLYKREGEPK

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01524.cif

Structure  SPKB01524.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2949.27244

Aliphatic index  71.15384615

Isoelectric point  6.576626495

Charge (pH=7)   0.000537236

Topological polar surface area  1268.15

Aromaticity  0.115384615

Average rotatable bonds  3.653846154

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  41

X logP energy  -13.22713

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.