SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01523

Signal sequence   IPLVANVSFNSDNGSQWLYKREEEPK

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01523.cif

Structure  SPKB01523.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3021.33604

Aliphatic index  71.15384615

Isoelectric point  4.587621972

Charge (pH=7)   -0.997687641

Topological polar surface area  1305.45

Aromaticity  0.115384615

Average rotatable bonds  3.769230769

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  42

X logP energy  -12.99373

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.