SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01521

Signal sequence   IPLVANVSFNSDNGSQWLYKREEGEK

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01521.cif

Structure  SPKB01521.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2981.27124

Aliphatic index  71.15384615

Isoelectric point  4.587621972

Charge (pH=7)   -0.997687641

Topological polar surface area  1314.24

Aromaticity  0.115384615

Average rotatable bonds  3.807692308

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  42

X logP energy  -13.86853

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.