SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01509

Signal sequence   IPLVANVSFNSDNGSQWLYKEGEPK

Length  25

Organism  Artificial

UniProt ID  NA,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01509.cif

Structure  SPKB01509.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2793.08494

Aliphatic index  74

Isoelectric point  4.426405943

Charge (pH=7)   -0.999459453

Topological polar surface area  1177.15

Aromaticity  0.12

Average rotatable bonds  3.56

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  39

X logP energy  -11.9752

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.