SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01494

Signal sequence   IPLVANVSFNSDNGSQWLYEEGEP

Length  24

Organism  Artificial

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01494.cif

Structure  SPKB01494.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2665.85224

Aliphatic index  77.08333333

Isoelectric point  3.331705025

Charge (pH=7)   -3.997094262

Topological polar surface area  1133.31

Aromaticity  0.125

Average rotatable bonds  3.416666667

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -11.8532

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.