SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01472

Signal sequence   IPLVANVSFNSDNGSQWLYKRGEK

Length  24

Organism  Artificial

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01472.cif

Structure  SPKB01472.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2723.04024

Aliphatic index  77.08333333

Isoelectric point  9.255260562

Charge (pH=7)   0.998762113

Topological polar surface area  1181.44

Aromaticity  0.125

Average rotatable bonds  3.708333333

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  38

X logP energy  -12.56773

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.