SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01466

Signal sequence   IPLVANVSFNSDNGSQWLYKREEK

Length  24

Organism  Artificial

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01466.cif

Structure  SPKB01466.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2795.10384

Aliphatic index  77.08333333

Isoelectric point  6.576626495

Charge (pH=7)   0.000537236

Topological polar surface area  1218.74

Aromaticity  0.125

Average rotatable bonds  3.833333333

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  39

X logP energy  -12.33433

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.