SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01464

Signal sequence   IPLVANVSFNSDNGSQWLYKREEE

Length  24

Organism  Artificial

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01464.cif

Structure  SPKB01464.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2796.04524

Aliphatic index  77.08333333

Isoelectric point  4.147551742

Charge (pH=7)   -1.997392608

Topological polar surface area  1230.02

Aromaticity  0.125

Average rotatable bonds  3.791666667

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  39

X logP energy  -12.59853

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.