SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01454

Signal sequence   IPLVANVSFNSDNGSQWLYEEGP

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01454.cif

Structure  SPKB01454.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2536.73674

Aliphatic index  80.43478261

Isoelectric point  3.424711863

Charge (pH=7)   -2.998869385

Topological polar surface area  1066.91

Aromaticity  0.130434783

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  35

X logP energy  -11.2028

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.